Suggested positive control: human lymphoblasts for IHC, human and mouse brain for Western blot.
LRRK2 is a member of the leucine-rich repeat kinase family and is a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: augmented in rheumatoid arthritis 17; AURA17; DARDARIN; leucine-rich repeat kinase 2; Leucine-rich repeat serine/threonine-protein kinase 2; PARK8; RIPK7; ROCO2
Gene Aliases: 4921513O20Rik; 9330188B09Rik; AURA17; AW561911; cI-46; D630001M17Rik; DARDARIN; Gm927; LRRK2; PARK8; RIPK7; ROCO2