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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues N(2506)LEKHIEVRKELAEKMR(2522) of human LRRK2.|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
The target sequence has 88% sequence homology with mouse and rat.
Suggested positive control: human brain lysate.
The novel LRRK2 gene (also known as PARK8), is responsible for up to 6% of all autosomal dominant Parkinson's disease (PD). LRRK2 missense mutations segregate with PARK8-linked PD and are implicated in other neurodegenerative diseases involving alpha-synuclein and tau pathology.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
augmented in rheumatoid arthritis 17; AURA17; DARDARIN; leucine-rich repeat kinase 2; PARK8; RIPK7; ROCO2
AURA17; DARDARIN; LRRK2; PARK8; RIPK7; ROCO2