Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:200 | - |
Immunohistochemistry (Frozen) (IHC (F)) |
1:400 | - |
Immunocytochemistry (ICC/IF) |
Assay-dependent | - |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Peptide corresponding to amino acid residues 183-196 of mouse LRRK2 (N-terminus) |
Conjugate |
Unconjugated |
Form |
Lyophilized |
Concentration |
0.8 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.4, with 1% BSA |
Contains |
0.05% sodium azide |
Storage conditions |
-20°C |
RRID |
AB_2857267 |
Reconstitute antibody with 50 µL of double distilled water (DDW). The reconstituted solution can be stored at 4 degrees C for up to 1 week. For longer periods, small aliquots should be stored at -20 degrees C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Peptide sequence is: CKALHVLFER VSEE
Homology: Rat, human amino acid residues are identical.
This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: augmented in rheumatoid arthritis 17; BC 300-268; Dardarin; DKFZp434H2111; FLJ45829; leucine-rich repeat kinase 2; Leucine-rich repeat serine/threonine-protein kinase 2; LRR kinase 2; LRRK 2; LRRK-2
Gene Aliases: 4921513O20Rik; 9330188B09Rik; AURA17; AW561911; cI-46; D630001M17Rik; DARDARIN; Gm927; LRRK2; PARK8; RIPK7; ROCO2
UniProt ID: (Human) Q5S007, (Mouse) Q5S006
Entrez Gene ID: (Human) 120892, (Mouse) 66725, (Rat) 300160
Molecular Function:
scaffold/adaptor protein
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