Keep as concentrated solution.
Positive Control: NT2D1, IMR32, U87-MG, MCF-7, mouse cerebellum.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: augmented in rheumatoid arthritis 17; augmented in rheumatoid arthritis 17 antibody; AURA17 antibody; Dardarin; DARDARIN antibody; leucine-rich repeat kinase 2; leucine-rich repeat kinase 2 antibody; Leucine-rich repeat serine/threonine-protein kinase 2; leucine-rich repeat serine/threonine-protein kinase 2 antibody; LRRK2 antibody; PARK8 antibody; RIPK7 antibody; ROCO2 antibody
Gene Aliases: 4921513O20Rik; 9330188B09Rik; AURA17; AW561911; cI-46; D630001M17Rik; DARDARIN; Gm927; LRRK2; PARK8; RIPK7; ROCO2