Invitrogen

LRRTM1 Polyclonal Antibody

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LRRTM1 Antibody in Immunohistochemistry (IHC) — Immunohistochemistry of LRRTM1 in human brain tissue with LRRTM1 Polyclonal Antibody (Product # PA5-21096) at 5 µg/mL.

LRRTM1 Antibody in Western Blot (WB) — Western Blot analysis of LRRTM1 in mouse brain tissue lysate with LRRTM1 Polyclonal Antibody (Product # PA5-21096) at 1 µg/mL in (A) the absence and (B) the presence of blocking peptide.

Product Details

PA5-21096

Applications	Tested Dilution	Publications
Western Blot (WB)	1 µg/mL	-
Immunohistochemistry (IHC)	5 µg/mL	-

Product Specifications
Species Reactivity	Human, Mouse, Rat
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	A 17 amino acid peptide near the carboxy terminus of human LRRTM1. View immunogen
Conjugate	Unconjugated
Form	Liquid
Concentration	1 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS
Contains	0.02% sodium azide
Storage conditions	Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
RRID	AB_11155007

Product Specific Information

A suggested positive control is SK-N-SH cell lysate.

PA5-21096 can be used with blocking peptide PEP-1210.

Target Information

The Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) are differentially expressed in the nervous system and were recently found to instruct presynaptic and mediate postsynaptic glutamatergic differentiation, with LRRTM1 and LRRTM2 most potent at inducing presynaptic differentiation. Each LRRTM protein is a type I transmembrane containing ten extracellular leucine-rich repeats and a short intracellular tail and has a developmentally regulated pattern distinct from all others. LRRTM1 is a maternally suppressed gene that is associated paternally with handedness and schizophrenia.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: leucine-rich repeat transmembrane neuronal 1; leucine-rich repeat transmembrane neuronal 1 protein; Leucine-rich repeat transmembrane neuronal protein 1

Gene Aliases: 4632401D06Rik; AW125451; LRRTM1; UNQ675/PRO1309

UniProt ID: (Rat) D4A6D8, (Human) Q86UE6, (Mouse) Q8K377

Entrez Gene ID: (Rat) 679668, (Human) 347730, (Mouse) 74342

Molecular Function: transmembrane signal receptor