Immunogen sequence: MNKRDYMNTS VQEPPLDYSF RSIHVIQDLV NEEPRTGLRP LKRSKSGKSL TQSLWLNNNV LNDLRDFNQV ASQLLEHPEN LAWIDLSFND LTSIDPV
Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 87%.
Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Required for auditory function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Catechol O-methyltransferase 2; leucine rich transmembrane and 0-methyltransferase domain containing; Leucine-rich repeat-containing protein 51; Protein LRTOMT1; Protein LRTOMT2; Transmembrane O-methyltransferase
Gene Aliases: CFAP111; COMT2; DFNB63; LRRC51; LRTOMT; PP7517; TOMT
UniProt ID: (Human) Q8WZ04
Entrez Gene ID: (Human) 220074
Molecular Function: methyltransferase