VEGF (Bevacizumab) Recombinant Human Monoclonal Antibody (A4.6.1), Functional Grade, Fc Muted™

fibronectin binding cytokine activity platelet-derived growth factor receptor binding vascular endothelial growth factor receptor binding protein binding growth factor activity heparin binding transmembrane receptor protein tyrosine kinase activator activity neuropilin binding chemoattractant activity identical protein binding protein homodimerization activity vascular endothelial growth factor receptor 1 binding vascular endothelial growth factor receptor 2 binding receptor agonist activity extracellular matrix binding

negative regulation of transcription from RNA polymerase II promoter angiogenesis ovarian follicle development blood vessel development patterning of blood vessels vasculogenesis response to hypoxia in utero embryonic development kidney development positive regulation of protein phosphorylation endothelial cell proliferation positive regulation of endothelial cell proliferation vasculature development lymphangiogenesis sprouting angiogenesis cell migration involved in sprouting angiogenesis positive regulation of neuroblast proliferation epithelial cell maturation positive regulation of receptor internalization immune system process basophil chemotaxis positive regulation of leukocyte migration heart morphogenesis outflow tract morphogenesis coronary vein morphogenesis regulation of transcription from RNA polymerase II promoter apoptotic process phospholipase C-activating G-protein coupled receptor signaling pathway nervous system development neuroblast proliferation mesoderm development lactation cell proliferation positive regulation of cell proliferation regulation of cell shape positive regulation of endothelial cell migration positive regulation of gene expression negative regulation of gene expression negative regulation of epithelial to mesenchymal transition regulation of nitric oxide mediated signal transduction cell migration negative regulation of cell-cell adhesion cell differentiation monocyte differentiation macrophage differentiation lung development positive regulation of cell migration epithelial cell differentiation post-embryonic camera-type eye development retinal ganglion cell axon guidance positive regulation of protein complex assembly positive regulation of protein autophosphorylation tube formation endothelial cell chemotaxis cellular response to vascular endothelial growth factor stimulus lymph vessel morphogenesis vascular endothelial growth factor receptor-2 signaling pathway positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway vascular endothelial growth factor signaling pathway positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway VEGF-activated neuropilin signaling pathway regulation of growth vasodilation eye photoreceptor cell development negative regulation of apoptotic process positive regulation of vascular permeability positive regulation of I-kappaB kinase/NF-kappaB signaling surfactant homeostasis positive regulation of MAPK cascade positive regulation of blood vessel endothelial cell migration endothelial cell migration negative regulation of fat cell differentiation regulation of endothelial cell differentiation positive regulation of osteoblast differentiation positive regulation of angiogenesis positive regulation of cell adhesion positive regulation of transcription from RNA polymerase II promoter vascular endothelial growth factor receptor signaling pathway cell maturation blood vessel morphogenesis camera-type eye morphogenesis positive regulation of axon extension involved in axon guidance artery morphogenesis homeostasis of number of cells within a tissue epithelial cell proliferation positive regulation of epithelial cell proliferation positive regulation of peptidyl-tyrosine phosphorylation positive chemotaxis positive regulation of positive chemotaxis induction of positive chemotaxis positive regulation of cell division positive regulation of focal adhesion assembly positive regulation of protein kinase B signaling cardiac muscle cell development primitive erythrocyte differentiation bone trabecula formation lung vasculature development mammary gland alveolus development positive regulation of mast cell chemotaxis cardiac vascular smooth muscle cell development coronary artery morphogenesis vascular wound healing bone trabecula morphogenesis positive regulation of ERK1 and ERK2 cascade cellular response to hypoxia dopaminergic neuron differentiation commissural neuron axon guidance positive regulation of cell migration involved in sprouting angiogenesis positive regulation of branching involved in ureteric bud morphogenesis motor neuron migration cellular stress response to acid chemical cell-cell adhesion positive regulation of cold-induced thermogenesis positive regulation of vascular endothelial growth factor signaling pathway positive regulation of trophoblast cell migration positive regulation of lymphangiogenesis regulation of hematopoietic progenitor cell differentiation negative regulation of pri-miRNA transcription from RNA polymerase II promoter positive regulation of protein localization to early endosome negative regulation of establishment of endothelial barrier negative regulation of adherens junction organization positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis positive regulation of sprouting angiogenesis positive regulation of epithelial tube formation positive regulation of blood vessel branching negative regulation of blood-brain barrier permeability negative regulation of cell-cell adhesion mediated by cadherin positive regulation of DNA biosynthetic process positive regulation of endothelial cell chemotaxis