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Product Details
PA5-61828
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human LTB. Recombinant protein control fragment (Product #RP-100090).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2643595
Product Specific Information
Immunogen sequence: GGLVTETADP GAQAQQGLGF QKLPEEEPET DLSPGLPAAH LIGAPLKGQG LGWETTKEQA FLTSGTQFSD
Highest antigen sequence identity to the following orthologs: Mouse - 53%, Rat - 53%.
Target Information
Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 molecule alpha/2 molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: LT-beta; lymphotoxin beta (TNF superfamily, member 3); Lymphotoxin-beta; TNF superfamily member 3; TNF-C; Tumor necrosis factor C; tumor necrosis factor ligand 1C; Tumor necrosis factor ligand superfamily member 3
Gene Aliases: LTB; p33; TNFC; TNFSF3; TNLG1C
UniProt ID: (Human) Q06643
Entrez Gene ID: (Human) 4050
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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