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|Tested species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Recombinant human lymphotoxin betaR extracellular domain, expressed in mouse NSO cells.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS with 5% trehalose|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|ELISA (ELISA)||0.5-1 µg/ml|
|Flow Cytometry (Flow)||Assay dependent|
|Western Blot (WB)||0.5-1 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-30176 detects LTBR from human samples.
PA1-30176 has been successfully used in flow cytometry, Western blot applications.
The PA1-30176 immunogen is: Recombinant human lymphotoxin betaR extracellular domain, expressed in mouse NSO cells.
The protein encoded by this gene is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including cells of epithelial and myeloid lineages, but not on T and B lymphocytes. The protein specifically binds the lymphotoxin membrane form (a complex of lymphotoxin-alpha and lymphtoxin-beta). The encoded protein and its ligand play a role in the development and organization of lymphoid tissue and tranformed cells. Activation of the encoded protein can trigger apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CD18; D12S370; LT-BETA-R; lymphotoxin B receptor; lymphotoxin beta receptor (TNFR superfamily, member 3); TNF-R-III; TNFCR; TNFR-RP; TNFR2-RP; TNFRSF3; tumor necrosis factor C receptor; tumor necrosis factor receptor 2-related protein; tumor necrosis factor receptor type III
CD18; D12S370; LT-BETA-R; LTBR; TNF-R-III; TNFCR; TNFR-RP; TNFR2-RP; TNFR3; TNFRSF3