Reconstitution information: Add 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
LUM is a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, this protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. The protein is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Keratan sulfate proteoglycan lumican; KSPG lumican; LDC; LUM; Lumican; lumican proteoglycan; SLRR2D
Gene Aliases: Lcn; LDC; LUM; SLRR2D