|Western Blot (WB)||1-3 µg/ml|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Goat / IgG|
|Immunogen||Internal sequence corresponding to amino acids CRLQDKKLPPLLSEI.|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with bovine and canine based on sequence homology.
Liver X receptors (LXRs), also known as RLD1, are oxysterol activated nuclear receptors which are involved in the regulation of genesis and metabolism of cholesterols and bile acids. LXRs form heterodimeric complexes with the retinoic acid receptors (RARs) once activated by their respective oxysterol ligands. Two known isoforms, alpha and beta, are differentially expressed; the alpha isoform predominantly expressed in liver, whereas beta isoform expression has been shown to be ubiquitous.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: liver X nuclear receptor alpha variant 1; liver X nuclear receptor beta; Liver X receptor alpha; Liver X receptor beta; liver X receptor, alpha; LX receptor beta; LXR alpha; LXR beta; LXR-a; LXR-b; LXRA; NER; NER-I; NR1H2; NR1H3; nuclear orphan receptor LXR-alpha; nuclear orphan receptor LXR-beta; nuclear rec; Nuclear receptor NER; Nuclear receptor subfamily 1 group H member 2; Nuclear receptor subfamily 1 group H member 3; nuclear receptor subfamily 1, group H, member 2; nuclear receptor subfamily 1, group H, member 3; Orphan nuclear receptor OR-1; Oxysterols receptor LXR-alpha; Oxysterols receptor LXR-beta; Retinoid X receptor-interacting protein No.15; RIP15; RLD-1; steroid hormone-nuclear receptor NER; ubiquitous receptor; Ubiquitously-expressed nuclear receptor; ubiquitously-expressed nuclear receptor 1; ubiquitously-expressed nuclear receptor 2; UR
Gene Aliases: AI194859; AU018371; LXR; LXR-a; LXR-b; LXRA; LXRalpha; LXRB; LXRbeta; NER; NER-I; NER1; NR1H2; NR1H3; OR-1; RIP15; RLD-1; RLD1; UNR; Unr1; Unr2; UR
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.