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Proteintech
LY6E Polyclonal Antibody
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Product Details
22144-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
LY6E Fusion Protein Ag17573 (21-101 aa encoded by BC119708)
Conjugate
Form
Liquid
Concentration
0.31 mg/mL
Amount
46.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: LMCFSCLNQ KSNLYCLKPT ICSDQDNYCV TVSASAGIGN LVTFGHSLSK TCSPACPIPE GVNVGVASMG ISCCQSFLCN FS (21-101 aa encoded by BC119708)
Target Information
Sca1, also known as Ly6A/E, is a member of the Ly6 multigene family of type V glycophosphatidylinositol anchored cell surface proteins. It is expressed on multipotent hematopoietic stem cells in bone marrow of mice with both the Ly6.1 and Ly6.2 allotypes. In the periphery, Sca1 exhibits a pattern of expression which is based on differences between the two allotypes. Ly6.1 strains (e.g., A, BALB/c, CBA, C3H/He, DBA/1, NZB) have few Sca1+ resting peripheral lymphocytes, whereas Ly6.2 strains (e.g., AKR, C57BL, C57BR, C57L, DBA/2, PL, SJL, SWR, 129) have relatively high numbers of Sca1+ lymphocytes. The expression of Sca1 is dramatically upregulated in all strains upon cellular activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: locus A/E; Locus AE; Ly-6E; Ly6A; lymphocyte antigen 6 complex, locus E; Lymphocyte antigen 6E; retinoic acid induced gene E; Retinoic acid-induced gene E protein; RIG-E; SCA-2; Stem cell antigen 2; Thymic shared antigen 1; TSA-1; unnamed protein product
Gene Aliases: 9804; Ly67; LY6E; RIG-E; RIGE; SCA-2; SCA2; TSA-1; TSA1
UniProt ID: (Human) Q16553, (Mouse) Q64253
Entrez Gene ID: (Human) 4061, (Mouse) 17069
cell surface receptor signaling pathway
negative regulation of viral entry into host cell
acetylcholine receptor signaling pathway
in utero embryonic development
adrenal gland development
organ growth
norepinephrine metabolic process
epinephrine secretion
ventricular cardiac muscle tissue morphogenesis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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