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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 217 of Human LYPLA3|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-31701 targets LYPLA3 in IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-31701 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 217 of Human LYPLA3.
Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene hydrolyzes lysophosphatidylcholine to glycerophosphorylcholine and a free fatty acid. This enzyme is present in the plasma and thought to be associated with high-density lipoprotein. A later paper contradicts the function of this gene. It demonstrates that this gene encodes a lysosomal enzyme instead of a lysophospholipase and has both calcium-independent phospholipase A2 and transacylase activities.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
1-O-acylceramide synthase; ACS; group XV phospholipase A2; GXVPLA2; LCAT-like lysophospholipase; LLPL; LPLA2; LYPLA3; lysophospholipase 3 (lysosomal phospholipase A2); lysosomal phospholipase A2; phospholipase A2, group XV
ACS; GXVPLA2; LLPL; LPLA2; LYPLA3; PLA2G15; UNQ341/PRO540