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          • Primary Antibodies ›
          • LZK Antibodies

          Invitrogen

          LZK Polyclonal Antibody

          View all (16) LZK antibodies

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          Cite LZK Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (1)
          LZK Antibody in Immunohistochemistry (IHC)
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          LZK Antibody in Immunohistochemistry (IHC)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          LZK Antibody (PA5-57772) in IHC

          Immunohistochemical staining of LZK in human kidney using a LZK Polyclonal Antibody (Product # PA5-57772) shows moderate membrane and cytoplasmic positivity in cells in tubules. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          View Product

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          LZK Antibody in Immunohistochemistry (IHC)
          LZK Polyclonal Antibody

          Product Details

          PA5-57772

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:200
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human LZK. Recombinant protein control fragment (Product #RP-97241).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.1 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2643649

          Product Specific Information

          Immunogen sequence: LADKLEDRLA EKLDDLLSQT PEIPIDISSH SDGLSDKECA VRRVKTQMSL GKLCVEERGY ENPMQFEESD CDSSDGECSD ATVRTNKHYS SATW

          Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 82%.

          Target Information

          Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine-like kinase (TLK) group consists of 40 tyrosine and serine-threonine kinases such as MLK (mixed-lineage kinase), LISK (LIMK/TESK), IRAK (interleukin-1 receptor-associated kinase), Raf, RIPK (receptor-interacting protein kinase), and STRK (activin and TGF-beta receptors) families.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Leucine zipper-bearing kinase; MAP3K13; Mitogen-activated protein kinase kinase kinase 13; Mixed lineage kinase; MLK

          View more View less

          Gene Aliases: LZK; MAP3K13; MEKK13; MLK

          View more View less

          UniProt ID: (Human) O43283

          View more View less

          Entrez Gene ID: (Human) 9175

          View more View less

          Function(s)
          protein serine/threonine kinase activity MAP kinase kinase kinase activity protein binding ATP binding protein kinase binding identical protein binding protein homodimerization activity metal ion binding non-receptor serine/threonine protein kinase
          Process(es)
          activation of MAPKK activity protein phosphorylation JNK cascade protein autophosphorylation positive regulation of NF-kappaB transcription factor activity
          It has to be done as per old AB suggested Products section.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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