This antibody is predicted to react with bovine, mouse and porcine based on sequence homology.
This gene encodes a member of the bone morphogenetic protein family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site that is cleaved to produce a mature protein containing seven conserved cysteine residues. Members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in yeast suggest that the encoded protein is involved in aging. This protein is transcribed from a monocistronic mRNA as well as a bicistronic mRNA, which also encodes growth differentiation factor 1.
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Protein Aliases: Ceramide synthase 1; CerS1; LAG1; LAG1 homolog, ceramide synthase 1; LAG1 longevity assurance homolog 1; LASS1; longevity assurance (LAG1, S. cerevisiae) homolog 1; longevity assurance gene 1; Longevity assurance gene 1 protein homolog 1; MGC90349; Protein UOG-1; UOG1; upstream of GDF1
Gene Aliases: CERS1; EPM8; LAG1; LASS1; UOG1
UniProt ID: (Human) P27544
Entrez Gene ID: (Human) 10715