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|Tested species reactivity||Human, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide (70 CTAEVLYPSTGQETAPE 86) of Latexin protein.|
|Storage buffer||whole serum with 50% glycerol|
|Contains||0.025% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Latexin, or tissue carboxypeptidase inhibitor (TCI), is the only known mammalian carboxypeptidase inhibitor. It is often related to a human putative tumor suppressor protein, TIG1. Latexin was first identified as a marker of neurons in the lateral neocortex of the developing mammalian brain. Latexin plays a role in the modulation of sensory perception and also functions in inflammation and innate immune pathways. The protein also contributes to the pathological disorders acute pancreatitis and lung inflammation. Latexin is expressed in heart, prostate, ovary, kidney, pancreas, colon and brain. The human latexin gene is assigned to chromosomal region 3q25.32.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
ECI; endogenous carboxypeptidase inhibitor; latexin; MUM; TCI; tissue carboxypeptidase inhibitor
ECI; LXN; TCI