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          • Primary Antibodies ›
          • LUM Antibodies

          Proteintech

          Lumican Polyclonal Antibody, CoraLite® Plus 488

          View all (19) LUM antibodies

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          Cite Lumican Polyclonal Antibody, CoraLite® Plus 488

          Additional Information:
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          • Antibody Testing Data (3)
          Lumican Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))
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          Lumican Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))
          Group 53 Created with Sketch.

          FIGURE: 1 / 3

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          Lumican Antibody (CL488-10677) in IHC (PFA)

          Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse spleen tissue using CoraLite® Plus 488 Lumican antibody (CL488-10677) at dilution of 1:200. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          Lumican Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))
          Lumican Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))
          Lumican Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))

          Product Details

          CL488-10677

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:500
          -

          Immunohistochemistry (PFA fixed) (IHC (PFA))

          1:200
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Lumican fusion protein Ag1106

          Conjugate

          CoraLite® Plus 488 CoraLite® Plus 488 CoraLite® Plus 488

          Excitation/Emission Max

          493/522 nm

          Form

          Liquid

          Concentration

          1 mg/mL

          Amount

          100 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol, 0.5% BSA

          Contains

          0.05% ProClin 300

          Storage conditions

          -20°C, store in dark

          Shipping conditions

          Wet ice

          Product Specific Information

          Immunogen sequence: MSLSAFTLF LALIGGTSGQ YYDYDFPLSI YGQSSPNCAP ECNCPESYPS AMYCDELKLK SVPMVPPGIK YLYLRNNQID HIDEKAFENV TDLQWLILDH NLLENSKIKG RVFSKLKQLK KLHINHNNLT ESVGPLPKSL EDLQLTHNKI TKLGSFEGLV NLTFIHLQHN RLKEDAVSAA FKGLKSLEYL DLSFNQIARL PSGLPVSLLT LYLDNNKISN IPDEYFKRFN ALQYLRLSHN ELADSGIPGN SFNVSSLVEL DLSYNKLKNI PTVNENLENY YLEVNQLEKF DIKSFCKILG PLSYSKIKHL RLDGNRISET SLPPDMYECL RVANEVTLN

          Target Information

          LUM is a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, this protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. The protein is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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          Cite this product

          Bioinformatics

          Protein Aliases: epididymis secretory sperm binding protein; Keratan sulfate proteoglycan lumican; KSPG lumican; Lumican; Lumican precursor; lumican proteoglycan; unnamed protein product

          View more View less

          Gene Aliases: Lcn; LDC; LUM; SLRR2D

          View more View less

          UniProt ID: (Human) P51884, (Rat) P51886, (Mouse) P51885

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          Entrez Gene ID: (Human) 4060, (Rat) 81682, (Mouse) 17022

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          Function(s)
          extracellular matrix structural constituent protein binding collagen binding extracellular matrix structural constituent conferring compression resistance molecular_function
          Process(es)
          visual perception response to organic cyclic compound collagen fibril organization positive regulation of transcription from RNA polymerase II promoter cartilage development response to growth factor positive regulation of transforming growth factor beta1 production response to Aroclor 1254
          It has to be done as per old AB suggested Products section.

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