Immunogen sequence: LPLEFPAGEK VNFITWLFNE TSLAFIVPHE TKSPEIHVTN PKQGKRLNFT QSYSLQLSNL KMEDTGSYRA QISTKT
Highest antigen sequence identity to the following orthologs: Mouse - 50%, Rat - 50%.
Ly108 is the mouse homologue of human SLAMF6 (signaling lymphocyte activation molecule family member 6). Mouse Ly108 is expressed on NK, B cells, and T cells. Activation of Ly108 receptor enhances NK cell activity and IFN-gamma expression.
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Protein Aliases: Activating NK receptor; CD352; KALI; natural killer-, T- and B-cell antigen; NK-T-B-antigen; NTB-A; NTBA receptor; SLAM family member 6; SLAMF6; UNQ6123/PRO20080
Gene Aliases: CD352; KALI; KALIb; Ly108; NTB-A; NTBA; SF2000; SLAMF6; UNQ6123/PRO20080
UniProt ID: (Human) Q96DU3
Entrez Gene ID: (Human) 114836
Molecular Function: cell adhesion molecule cytokine receptor defense/immunity protein immunoglobulin receptor superfamily kinase membrane-bound signaling molecule protein kinase protein kinase receptor receptor signaling molecule transferase tyrosine protein kinase receptor