Positive Samples: Jurkat, Mouse lung, Mouse spleen, Rat liver; Cellular Location: Cell membrane, Single-pass type I membrane protein
Ly108 is the mouse homologue of human SLAMF6 (signaling lymphocyte activation molecule family member 6). Mouse Ly108 is expressed on NK, B cells, and T cells. Activation of Ly108 receptor enhances NK cell activity and IFN-gamma expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Activating NK receptor; CD352; Lymphocyte antigen 108; natural killer-, T- and B-cell antigen; NK-T-B-antigen; NTB-A; NTBA receptor; SLAM family member 6
Gene Aliases: CD352; KAL1; KAL1b; KALI; KALIb; Ly108; NTB-A; NTBA; RGD1561848; SF2000; SLAMF6; UNQ6123/PRO20080
Molecular Function: cell adhesion molecule cytokine receptor defense/immunity protein immunoglobulin receptor superfamily kinase membrane-bound signaling molecule protein kinase protein kinase receptor receptor signaling molecule transferase tyrosine protein kinase receptor