This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated. View Details
Keep as concentrated solution.
Predicted reactivity: Mouse (95%), Rat (95%), Xenopus laevis (83%), Chicken (86%), Sheep (96%), Bovine (95%).
Positive Control: HeLa, THP-1, CD44-knockout HeLa.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Lyn proto oncogene (Lcl/Yes related novel protein tyrosine kinase) is encoded by the Lyn gene located on chromosome 8 in humans and belongs to the Src family kinase. It is a non-receptor tyrosine kinase that acts as a mediator in transducing cellular signaling. The most well studied expression of Lyn is in hematopoietic cell types, both lymphoid and myeloid cells with exclusion in T lymphocytes. It has also been observed that Lyn plays diverse roles such as in regulation of B cell receptor signaling, mast cell signaling and Epithelial - Mesenchymal Transition (EMT).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FLJ26625; Lck/Yes-related novel protein tyrosine kinase; lyn protein non-receptor kinase; p53Lyn; p56Lyn; Tyrosine-protein kinase Lyn; V-yes-1 Yamaguchi sarcoma viral related oncogene homolog; Yamaguchi sarcoma viral (v-yes-1) oncogene homolog
Gene Aliases: JTK8; LYN; p53Lyn; p56Lyn