Keep as concentrated solution.
Positive Control: HeLa, THP-1, CD44-knockout HeLa.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
Prohibitin is an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FLJ26625 antibody; JTK8 antibody; Lck/Yes-related novel protein tyrosine kinase; lck/Yes-related novel protein tyrosine kinase antibody; LYN antibody; p53Lyn; p56Lyn; Tyrosine-protein kinase Lyn; tyrosine-protein kinase Lyn antibody; V-yes-1 Yamaguchi sarcoma viral related oncogene homolog; v-yes-1 Yamaguchi sarcoma viral related oncogene homolog antibody
Gene Aliases: JTK8; LYN; p53Lyn; p56Lyn
UniProt ID: (Human) P07948
Entrez Gene ID: (Human) 4067