PA1-29512 detects MPR46 from mouse, human, rat samples.
M6PR is a receptor for mannose-6-phosphate groups on lysosomal enzymes. The receptor forms a homodimer or homotetramer for intracellular targeting of lysosomal enzymes and export of newly synthesized lysosomal enzymes into the cell secretions. The receptor is an integral membrane protein which localizes to the trans-Golgi reticulum, endosomes, and the plasma membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 46 kDa mannose 6-phosphate receptor; 46-kDa mannose 6-phosphate receptor; Cation-dependent mannose-6-phosphate receptor; CD Man-6-P receptor; CD-MPR; FLJ32994; mannose-6-phosphate receptor (cation dependent); MPR 46; Mr 46,000 Man6PR; small mannose 6-phosphate receptor
Gene Aliases: 46mpr; CD-M6PR; CD-MPR; M6PR; MPR 46; MPR-46; MPR46; MPRD; SMPR
Molecular Function: membrane traffic protein