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Invitrogen
Cytokeratin 17 Monoclonal Antibody (E3)
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FIGURE: 1 / 5
Cytokeratin 17 Antibody (MA1-06325) in ICC/IF
Immunofluorescence analysis of Cytokeratin 17 was performed using MCF 10A and MCF7 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 1 hour at room temperature. The cells were labeled with Cytokeratin 17 Monoclonal Antibody (Product # MA1-06325) at 1:100 dilution in 0.1% BSA and incubated overnight at 4 degr... View More
Product Details
MA1-06325
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Published species
Human,
Mouse
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
E3
Immunogen
Cytoskeletal preparation from rat colon.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
purified
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
MA1-06325 detects cytokeratin 17 in human and rat samples.
MA1-06325 has sucessfully been used in Western blotting, flow cytometry, immunocytochemistry, and immunohistochemistry.
The MA1-06325 immunogen is a cytoskeletal preparation from rat colon.
Target Information
Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between approximately40 kDa and approximately68 kDa and isoelectric pH between 4. 9 - 7. 8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 39.1; CK-17; CK17; Cytokeratin-17; hard keratin; HLA-DRB1-restricted epitope S1; HLA-DRB1-restricted epitope S2; HLA-DRB1-restricted epitope S3; HLA-DRB1-restricted epitope S4; K17; keratin 17, type I; Keratin, type I cytoskeletal 17; Keratin-17; krt17 {ECO:0000250|UniProtKB:Q04695}; Type I keratin Ka17; unnamed protein product
Gene Aliases: 39.1; CK-17; K17; Ka17; KRT17; PC; PC2; PCHC1
UniProt ID: (Human) Q04695, (Rat) Q6IFU8
Entrez Gene ID: (Human) 3872, (Rat) 287702
morphogenesis of an epithelium
positive regulation of cell growth
epithelial cell differentiation
hair follicle morphogenesis
keratinization
intermediate filament organization
positive regulation of translation
positive regulation of hair follicle development
signal transduction
intermediate filament-based process
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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