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Invitrogen
CD2/CD7 Antibody Cocktail, FITC, PE
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Product Details
MA1-12005
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a
Class
Cocktail
Type
Antibody
Clone
T6.3, MG34
Immunogen
T lymphocytes activated by mixed lymphocyte culture and T-acute lymphoblastic leukemia (T-ALL) cells
Conjugate
Form
Liquid
Purification
Protein A/G
Storage buffer
PBS with 0.2% carrier protein
Contains
0.08% sodium azide
Storage conditions
4°C, store in dark, DO NOT FREEZE!
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is a monoclonal mixture of FITC-conjugated CD2 (clone T6.3, isotype IgG2a) and PE-conjugated CD7 (clone MG34, isotype IgG2a).
Target Information
Natural killer (NK) cells in teleosts and their evolutionary homologue are a subpopulation of lymphocytes with properties that distinguish them from either B- or T-cells. NK cells are important effectors of innate immunity where they release cytokines, which in turn up-regulate other immunological functions. Monoclonal antibodies have been used to identify different surface antigens present on NK cells. These surface antigens have not only been used to identify NK cells, but also their functionally distinct subsets. The Cluster of Differentiation (CD) nomenclature was established to standardize the naming of NK cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 2CD2 antigen; CD2; CD2 antigen (p50), sheep red blood cell receptor; CD2 surface antigen; CD7; CD7 antigen (p41); Erythrocyte receptor; GP40; LFA-2; LFA-3 receptor; lymphocyte-function antigen-2; p41 protein; Rosette receptor; surface antigen CD2 precursor; T-cell antigen CD7; T-cell leukemia antigen; T-cell surface antigen CD2; T-cell surface antigen CD2 precursor; T-cell surface antigen Leu-9; T-cell surface antigen T11/Leu-5; TP41; unnamed protein product
Gene Aliases: CD2; CD7; GP40; LEU-9; LFA-2; SRBC; T11; Tp40; TP41
UniProt ID: (Human) P06729, (Human) P09564
Entrez Gene ID: (Human) 914, (Human) 924
adaptive immune response
immune system process
positive regulation of T cell cytokine production
immune response
transmembrane receptor protein tyrosine kinase signaling pathway
interleukin-2-mediated signaling pathway
T cell activation
membrane raft polarization
apoptotic process
cell adhesion
cell surface receptor signaling pathway
natural killer cell activation
positive regulation of myeloid dendritic cell activation
positive regulation of interferon-gamma production
positive regulation of interleukin-8 production
positive regulation of tumor necrosis factor production
heterotypic cell-cell adhesion
natural killer cell mediated cytotoxicity
regulation of T cell differentiation
cell-cell adhesion
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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