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Invitrogen
FXR2 Monoclonal Antibody (1G2)
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FIGURE: 1 / 5
FXR2 Antibody (MA1-16767) in ICC/IF
Immunofluorescent analysis of FXR2 in A431 cells. The cells were fixed with 100% methanol for 15 minutes at -20C, permeabilized with 0.1% Triton X-100 for 15 minutes, and blocked with 3% BSA for 30 minutes at room temperature. Cells were stained with a FXR2 mouse monoclonal antibody (Product # MA1-16767) at a concentration of 5 µg/mL in blocking buffer overnight at 4C, and then incubated with a Goat anti-Mouse IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor® Plus 488 conjugate (Product # A32723) at a dilution of 1:500 for a... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA1-16767
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
1G2
Immunogen
Recombinant C-terminal fragment of human FXR2 (residues 414-658).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1.0 mg/mL
Amount
100 µg
Purification
Protein G
Storage buffer
PBS
Contains
0.01% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Suggested positive control: Hela whole cell extract, HeLa whole cell lysate.
Target Information
Fragile X syndrome is caused by the absence of the fragile X mental-retardation protein (FMRP). FMRP is the archetype of a class of cytoplasmic mRNA-binding proteins that includes the fragile X-related 1 and 2 proteins (FXR1 and FXR2). The fragile X-related proteins FXR1 and FXR2 contain a functional nucleolar-targeting signal equivalent to the HIV-1 regulatory proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Fxr2h; unnamed protein product
Gene Aliases: FMR1L2; Fxr2h; FXR2P
UniProt ID: (Human) P51116
Entrez Gene ID: (Human) 9513, (Mouse) 23879
regulation of translation
posttranscriptional regulation of gene expression
negative regulation of gene expression
dentate gyrus development
regulation of mRNA stability
positive regulation of translation
positive regulation of long-term neuronal synaptic plasticity
animal organ development
mRNA transport
mRNA destabilization
regulation of translation at presynapse, modulating synaptic transmission
regulation of mRNA metabolic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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