Search
Invitrogen
FXR2 Monoclonal Antibody (1G2)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
FIGURE: 1 / 5
FXR2 Antibody (MA1-16767) in ICC/IF
Immunofluorescent analysis of FXR2 in A431 cells. The cells were fixed with 100% methanol for 15 minutes at -20C, permeabilized with 0.1% Triton X-100 for 15 minutes, and blocked with 3% BSA for 30 minutes at room temperature. Cells were stained with a FXR2 mouse monoclonal antibody (Product # MA1-16767) at a concentration of 5 µg/mL in blocking buffer overnight at 4C, and then incubated with a Goat anti-Mouse IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor® Plus 488 conjugate (Product # A32723) at a dilution of 1:500 for a... View More
Product Details
MA1-16767
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
1G2
Immunogen
Recombinant C-terminal fragment of human FXR2 (residues 414-658).
Conjugate
Form
Liquid
Concentration
1.0 mg/mL
Amount
100 µg
Purification
Protein G
Storage buffer
PBS
Contains
0.01% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Suggested positive control: Hela whole cell extract, HeLa whole cell lysate.
Target Information
Fragile X syndrome is caused by the absence of the fragile X mental-retardation protein (FMRP). FMRP is the archetype of a class of cytoplasmic mRNA-binding proteins that includes the fragile X-related 1 and 2 proteins (FXR1 and FXR2). The fragile X-related proteins FXR1 and FXR2 contain a functional nucleolar-targeting signal equivalent to the HIV-1 regulatory proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: FMR1 autosomal homolog 2; fragile X mental retardation gene 2, autosomal homolog; fragile X mental retardation syndrome-related protein 2; fragile X mental retardation-related protein 2; FXR2P; RNA-binding protein FXR2; unnamed protein product
Gene Aliases: FMR1L2; FXR2; Fxr2h; FXR2P
UniProt ID: (Human) P51116
Entrez Gene ID: (Human) 9513, (Mouse) 23879
regulation of translation
dentate gyrus development
regulation of mRNA stability
positive regulation of translation
positive regulation of long-term neuronal synaptic plasticity
animal organ development
mRNA transport
mRNA destabilization
regulation of translation at presynapse, modulating synaptic transmission
positive regulation of defense response to virus by host
negative regulation of translation
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support