Search
Invitrogen
Thyroid Stimulating Hormone Monoclonal Antibody (TSH-116)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Product Details
MA1-19067
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
TSH-116
Immunogen
Human thyrotropin.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
15mM sodium azide
Storage conditions
4°C, do not freeze
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody reacts with association constant 1.1 x 1011 l/mol. Following cross-reactivity expressed as binding of labelled hormone (% of total) was determined by solid phase RIA with excess of the antibody TSH-116: hTSH (78.9), hCG (20.3), hLH (23.2), hFSH (29.9).
Target Information
The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: anterior pituitary glycoprotein hormones common subunit alpha; CGA; choriogonadotropin alpha chain; chorionic gonadotrophin subunit alpha; chorionic gonadotropin, alpha polypeptide; follicle-stimulating hormone alpha chain; follicle-stimulating hormone alpha subunit; follitropin alpha chain; FSH-alpha; LSH-alpha; luteinizing hormone alpha chain; lutropin alpha chain; thyroid stimulating hormone beta; thyroid-stimulating hormone alpha chain; Thyrotropin; thyrotropin alpha chain; thyrotropin beta chain; TSH-alpha; unnamed protein product
Gene Aliases: CG-ALPHA; FSHA; GPA1; GPHa; GPHA1; HCG; LHA; TSH-B; TSH-BETA; TSHA
UniProt ID: (Human) P01215, (Human) P01222
Entrez Gene ID: (Human) 1081, (Human) 7252
signal transduction
G-protein coupled receptor signaling pathway
cell-cell signaling
anatomical structure morphogenesis
hormone-mediated signaling pathway
MAPK cascade
ovarian follicle development
spermatogenesis
positive regulation of cell proliferation
regulation of receptor activity
positive regulation of steroid biosynthetic process
positive regulation of cell migration
insulin secretion involved in cellular response to glucose stimulus
follicle-stimulating hormone signaling pathway
positive regulation of transcription from RNA polymerase II promoter
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support