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Invitrogen
Cardiac Troponin T Monoclonal Antibody (7E7)
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FIGURE: 1 / 1
Cardiac Troponin T Antibody (MA1-20879) in ELISA
ELISA calibration curves for sandwich cTnT fluoroimmunoassay with different animal TnTs as antigen. (dark blue) canine, (blue/grey) human, (grey) mouse, (black) rat. Monoclonal antibodies: Capture, Cardiac Troponin T Monoclonal Antibody (clone 1C11), 1 g/well. Detection: Cardiac Troponin T Monoclonal Antibody (7E7) (Product # MA1-20879).
Product Details
MA1-20879
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
7E7
Immunogen
Human Tn complex.
Conjugate
Form
Liquid
Concentration
5.2 mg/mL
Amount
200 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
MA1-20879 detects Cardiac Troponin T in Human samples.
Target Information
Cardiac Troponin T is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Cardiac Troponin T is important in proper muscle function and myofibril formation. In the human heart, four cTnT isoforms are expressed in a developmentally regulated manner. Cardiac Troponin T expression in the human heart is affected by heart failure. Mutations within the Cardiac Troponin T protein have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for the Cardiac Troponin T gene undergo alternative splicing that results in many tissue-specific isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cardiac muscle troponin T; cardiomyopathy, dilated 1D (autosomal dominant); cardiomyopathy, hypertrophic 2; cTnT; MGC3889; TnTc; troponin T; troponin T type 2 (cardiac); Troponin T, cardiac muscle; Troponin T2; unnamed protein product
Gene Aliases: CMD1D; CMH2; CMPD2; cTnT; LVNC6; RCM3; TNNT2; TnTC
UniProt ID: (Human) P45379
Entrez Gene ID: (Human) 7139
regulation of muscle contraction
striated muscle contraction
regulation of heart contraction
muscle filament sliding
negative regulation of ATPase activity
positive regulation of ATPase activity
sarcomere organization
response to calcium ion
ventricular cardiac muscle tissue morphogenesis
cardiac muscle contraction
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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