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Invitrogen
Apolipoprotein A5 Monoclonal Antibody (4H8H8E2)
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FIGURE: 1 / 2
Apolipoprotein A5 Antibody (MA1-46077) in ICC/IF
Immunofluorescence analysis of Apolipoprotein A5 was performed using 70% confluent log phase HepG2 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 10 minutes, and blocked with 1% BSA for 1 hour at room temperature. The cells were labeled with Apolipoprotein A5 (4H8H8E2) Mouse Monoclonal Antibody (Product # MA1-46077) at 2 µg/mL in 0.1% BSA and i... View More
Product Details
MA1-46077
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
4H8H8E2
Immunogen
Ni-NTA purified full-length recombinant human Apolipoprotein A5 expressed in E. Coli strain BL21 (DE3).
Conjugate
Form
Liquid
Concentration
1.2 mg/mL
Amount
120 µg
Purification
Protein G
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Suggested positive control: antigen standard for APOA5 (transient overexpression lysate).
Target Information
Apolipoprotein A4 (also known as ApoA-IV) is a plasma protein that is O-linked glycoprotein after proteolytic processing. ApoA4 is a major constituent of HDL and it also can be found on the surface of newly synthesized chylomicrons. The physiological function of ApoA4 is not completely identified so far, but several evidences from vitro studies indicate that this apolipoprotein involves in several steps of the reverse cholesterol transport pathway, which transports cholesterol from peripheral cells back to the liver.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Apo-AV; Apolipoprotein A-V; Apolipoprotein A5; apolipoprotein AV; FLJ97995; MGC126836; MGC126838; Regeneration-associated protein 3; unnamed protein product
Gene Aliases: APOA5; APOAV; RAP3; UNQ411/PRO773
UniProt ID: (Human) Q6Q788
Entrez Gene ID: (Human) 116519
protein binding
phospholipid binding
heparin binding
lipid binding
enzyme binding
phosphatidylcholine binding
lipase binding
low-density lipoprotein particle receptor binding
phosphatidylcholine-sterol O-acyltransferase activator activity
lipase activator activity
lipoprotein lipase activator activity
lipoprotein particle receptor binding
intermembrane cholesterol transfer activity
triglyceride metabolic process
lipid transport
cholesterol metabolic process
positive regulation of triglyceride catabolic process
positive regulation of very-low-density lipoprotein particle remodeling
triglyceride catabolic process
cholesterol efflux
phospholipid efflux
triglyceride-rich lipoprotein particle remodeling
very-low-density lipoprotein particle clearance
lipoprotein metabolic process
tissue regeneration
cholesterol homeostasis
positive regulation of fatty acid biosynthetic process
positive regulation of receptor-mediated endocytosis
positive regulation of lipid catabolic process
acylglycerol homeostasis
triglyceride homeostasis
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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