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Invitrogen
CD31 Monoclonal Antibody (CO.3E1D4), FITC
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FIGURE: 1 / 1
CD31 Antibody (MA1-80360) in Flow
Frontiers in cell and developmental biology 2022 -
FIGURE 4 Mesothelial cells are a VAT-specific cell type. (A) UMAP plot of ME across visceral (VAT) and subcutaneous (SAT) adipose tissue of dairy cows (n = 3) obtained through snRNA-seq analysis. (B) Violin plots of ME marker genes MSLN, KRT19, WT1 and UPK3B in ME subtypes. The y axis indicates log-transformed expression values, and the width indicates the number of cells expressing the gene. (C) UMAP plots... View More
Product Details
MA1-80360
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Goat,
Sheep
Published species
Bovine
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
CO.3E1D4
Immunogen
Ovine leucocytes.
Conjugate
Excitation/Emission Max
498/517 nm
View spectra
Form
Liquid
Concentration
0.1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
For FACS analysis, use 10 µL of the suggested working dilution to label 1x10^6 cells in 100 µL.
Mouse anti Sheep CD31 antibody, clone CO.3E1D4 recognizes ovine CD31, also known as PECAM-1.Ovine CD31 is predominantly expressed by peripheral blood platelets and a small percentage of lymphocytes.
Target Information
CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases. CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells. N-terminal Ig-like domain of CD31 is responsible for its homophilic binding, which plays an important role in cell-cell interactions. CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. It is one of key regulatory molecules in vascular system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
How to use the Panel Builder
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Bioinformatics
Protein Aliases: CD31 antigen; PECAM-1; platelet/endothelial cell adhesion molecule (CD31 antigen)
Entrez Gene ID: (Goat) 102179808, (Bovine) 282303, (Sheep) 100303608
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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