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Invitrogen
CD105 Monoclonal Antibody (SN6), PE
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FIGURE: 1 / 1
CD105 Antibody (MA1-80944) in Flow
PloS one 2019 -
Fig 1 MSCs derived from horse peripheral blood expressed typical MSC markers and reduced lameness in horses with osteoarthritis. (A) Representative phenotype of MSC, gray line represents unstained cells; the red filled line represents cells stained with individual specific antibodies (CD105, CD146, CD90, CD73). (B) The AAEP lameness scale was used for grading lameness before and after six weeks. Autologous ... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA1-80944
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Horse,
Human,
Non-human primate
Published species
Human,
Mouse
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
SN6
Immunogen
Cell membrane antigens from fresh leukemia cells.
Conjugate
PE
PE
PE
Excitation/Emission Max
565/576 nm
View spectra
Form
Lyophilized
Concentration
Conc. Not Determined
Purification
Protein A
Storage buffer
PBS, pH 7.4, with 1% BSA, 5% sucrose
Contains
0.09% sodium azide
Storage conditions
4°C, store in dark, DO NOT FREEZE!
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute with 1 mL of distilled water. After reconstitution, store product undiluted at 4°C in the dark.
For FACS analysis, use 10 µL of the suggested working dilution to label 1x10^6 cells in 100 µL.
Mouse anti Human CD105 antibody, clone SN6 recognizes the human endoglin, also known as CD105. CD105 is a glycoprotein homodimer of approximately 95 kDa subunits expressed by endothelial cells, activated monocytes and some leukemia cells.
Target Information
CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD105; Endoglin; endoglin (Osler-Rendu-Weber syndrome 1); ORW
Gene Aliases: CD105; END; ENG
Entrez Gene ID: (Horse) 100070421
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