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For FACS analysis, use 10 µL of the suggested working dilution to label 1x10^6 cells in 100 µL. For FACS testing, we recommend incubation times of at least 30 minutes with this antibody.
Mouse anti Human CD79a antibody, clone ZL7-4 recognizes the human B-cell antigen receptor complex-associated protein alpha chain, also known as MB-1 membrane glycoprotein or CD79a.
CD79a is a disulphide-linked heterodimer that includes B29 (CD79b) polypeptide. CD79a is a B lymphocyte antigen receptor with an antigen-specific surface component Ig (immunoglobulin) that associates with Ig-alpha and Ig-beta, necessary elements for the expression and function of the B-cell antigen receptor. CD79a first appears at pre-B cell stage and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type, in B cell lines, B cell lymphomas, and in some myelomas. It is not present in myeloid or T cell lines. Diseases associated with CD79a include Agammaglobulinemia 3 and Agammaglobulinemia, Non-Bruton type.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Protein Aliases: B-cell antigen receptor complex-associated protein alpha chain; CD79; CD79a; CD79a antigen (immunoglobulin-associated alpha); CD79a molecule, immunoglobulin-associated alpha; extracellular domain; Ig-alpha; MB-1 membrane glycoprotein; membrane-bound immunoglobulin associated protein; Membrane-bound immunoglobulin-associated protein; signal transduction via sig in B lymphocytes; putative; similar to Homo sapiens CD79A antigen (immunoglobulin-associated alpha) encoded by GenBank Accession Number U05259; Surface IgM-associated protein; unnamed protein product
Gene Aliases: CD79A; IGA; IGAlpha; MB-1; MB1
UniProt ID: (Human) P11912
Entrez Gene ID: (Human) 973
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