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Suggested positive control: NIH-3T3 whole cell lysates.
PDCD7 is a protein with sequence similarity to a mouse protein originally identified in embryonic stem cells. In mouse T-cell lines, this protein appears to be related to glucocorticoid- and staurine-induced apoptotic pathways, and to be linked to ceramide-mediated signaling. These observations suggest that this gene product is involved in specific apoptotic processes in T-cells. This gene encodes a protein with sequence similarity to a mouse protein originally identified in embryonic stem cells. In mouse T-cell lines, this protein appears to be related to glucocorticoid- and staurine-induced apoptotic pathways, and to be linked to ceramide-mediated signaling. These observations suggest that this gene product is involved in specific apoptotic processes in T-cells.
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Protein Aliases: H MGC22015; MGC22015; programmed cell death protein 7
Gene Aliases: C80112; ES18
Entrez Gene ID: (Mouse) 50996
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