GSK3 alpha/beta Monoclonal Antibody (4G-1E)

nucleotide binding protein kinase activity protein serine/threonine kinase activity receptor binding protein binding ATP binding kinase activity transferase activity protein kinase A catalytic subunit binding tau protein binding tau-protein kinase activity protein serine kinase activity protease binding p53 binding beta-catenin binding protein kinase binding ubiquitin protein ligase binding dynactin binding NF-kappaB binding RNA polymerase II sequence-specific DNA binding transcription factor binding scaffold protein binding transferase activity, transferring phosphorus-containing groups RNA polymerase II transcription factor binding integrin binding transcription factor binding ionotropic glutamate receptor binding cyclin-dependent protein serine/threonine kinase activity RNA polymerase II carboxy-terminal domain kinase activity non-receptor serine/threonine protein kinase

regulation of systemic arterial blood pressure cardiac left ventricle morphogenesis glycogen metabolic process nervous system development insulin receptor signaling pathway negative regulation of signal transduction positive regulation of autophagy positive regulation of gene expression negative regulation of UDP-glucose catabolic process regulation of neuron projection development Wnt signaling pathway cell migration viral protein processing cell differentiation positive regulation of protein ubiquitination lipopolysaccharide-mediated signaling pathway negative regulation of TOR signaling positive regulation of proteasomal ubiquitin-dependent protein catabolic process cellular response to insulin stimulus cellular response to interleukin-3 proteasome-mediated ubiquitin-dependent protein catabolic process positive regulation of neuron apoptotic process negative regulation of glycogen biosynthetic process positive regulation of protein catabolic process positive regulation of heart contraction positive regulation of transcription from RNA polymerase II promoter negative regulation of glucose import negative regulation of insulin receptor signaling pathway excitatory postsynaptic potential negative regulation of cell growth involved in cardiac muscle cell development regulation of microtubule cytoskeleton organization cellular response to lithium ion cellular response to glucocorticoid stimulus positive regulation of adrenergic receptor signaling pathway negative regulation of canonical Wnt signaling pathway extrinsic apoptotic signaling pathway extrinsic apoptotic signaling pathway in absence of ligand positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway autosome genomic imprinting beta-arrestin-dependent dopamine receptor signaling pathway positive regulation of substrate adhesion-dependent cell spreading positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway regulation of mitophagy cellular response to oxygen-containing compound positive regulation of beta-amyloid formation positive regulation of protein targeting to mitochondrion positive regulation of establishment of protein localization negative regulation of type B pancreatic cell development negative regulation of glycogen (starch) synthase activity G1/S transition of mitotic cell cycle epithelial to mesenchymal transition positive regulation of cell-matrix adhesion cytoplasmic translational initiation heart valve development protein phosphorylation ER overload response mitochondrion organization regulation of mitotic cell cycle circadian rhythm negative regulation of gene expression negative regulation of epithelial to mesenchymal transition peptidyl-serine phosphorylation hippocampus development establishment of cell polarity maintenance of cell polarity positive regulation of cell migration negative regulation of cell migration regulation of axon extension SCF-dependent proteasomal ubiquitin-dependent protein catabolic process neuron projection development negative regulation of protein complex assembly positive regulation of protein complex assembly positive regulation of protein binding negative regulation of proteasomal ubiquitin-dependent protein catabolic process regulation of microtubule-based process response to endoplasmic reticulum stress intracellular signal transduction TORC2 signaling regulation of circadian rhythm negative regulation of apoptotic process protein kinase B signaling positive regulation of cell differentiation negative regulation of osteoblast differentiation positive regulation of cilium assembly positive regulation of translation protein autophosphorylation regulation of protein export from nucleus positive regulation of protein export from nucleus rhythmic process regulation of dendrite morphogenesis regulation of axonogenesis positive regulation of protein kinase B signaling canonical Wnt signaling pathway negative regulation of calcineurin-NFAT signaling cascade superior temporal gyrus development cellular response to retinoic acid presynaptic modulation of chemical synaptic transmission neuron projection organization membraneless organelle assembly regulation of microtubule anchoring at centrosome regulation of cellular response to heat negative regulation of protein localization to nucleus regulation of long-term synaptic potentiation negative regulation of extrinsic apoptotic signaling pathway via death domain receptors positive regulation of protein localization to cilium negative regulation of TORC2 signaling negative regulation of dopaminergic neuron differentiation cellular response to beta-amyloid positive regulation of protein localization to centrosome negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process negative regulation of mesenchymal stem cell differentiation regulation of gene expression by genetic imprinting signal transduction positive regulation of peptidyl-threonine phosphorylation positive regulation of cAMP biosynthetic process positive regulation of peptidyl-serine phosphorylation hypermethylation of CpG island negative regulation of transferase activity cellular response to organic cyclic compound positive regulation of glycogen (starch) synthase activity carbohydrate metabolic process phosphorylation regulation of mitophagy re-entry into mitotic cell cycle protein export from nucleus cytoskeleton organization establishment or maintenance of cell polarity multicellular organism development axonogenesis myoblast fusion cell proliferation organ morphogenesis negative regulation of cardiac muscle hypertrophy negative regulation of neuron projection development negative regulation of neuron maturation myotube differentiation negative regulation of protein binding protein localization to microtubule positive regulation of apoptotic process negative regulation of MAP kinase activity positive regulation of GTPase activity canonical Wnt signaling pathway involved in positive regulation of apoptotic process fat cell differentiation positive regulation of axon extension regulation of neuronal synaptic plasticity negative regulation of dendrite morphogenesis negative regulation of NFAT protein import into nucleus cellular response to mechanical stimulus positive regulation of stem cell differentiation response to lithium ion response to drug regulation of cell cycle male gamete generation