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Invitrogen
TIMP2 Monoclonal Antibody (3A4)
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Product Details
MA5-12207
Applications
Tested Dilution
Publications
Product Specifications
Published species
Bovine,
Human,
Mouse,
Rabbit,
Rat
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
3A4
Immunogen
A synthetic peptide from the N-terminal region of human TIMP-2 protein
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
MA5-12207 targets TIMP-2 in IHC (P) and WB applications and shows reactivity with Bovine, Guinea Pig, Human, mouse, Rabbit, and Rat samples.
The MA5-12207 immunogen is a synthetic peptide from the N-terminal region of human TIMP-2 protein.
Target Information
TIMP-1 and TIMP-2 are inhibitory enzymes of matrix metalloproteinase family, and are thought to be of great importance in the maintenance of connective tissue integrity. TIMP-2 shows the highest binding affinity to both the latent (pro) and active forms of 72 kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92 kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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