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Invitrogen
Collagen II Monoclonal Antibody (2B1.5), Biotin
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FIGURE: 1 / 1
Collagen II Antibody (MA5-12786) in ICC/IF
Nature 2012 -
Figure 2 Reprogramming non-cardiomyocytes toward a cardiac fate in vivo by GHMT a. Heart sections of Fsp1-cre/Rosa26-LacZ mice uninjured or three weeks post-MI followed by injection of GFP or GHMT retroviruses. GFP-infected myocardium showed only beta-gal + non-cardiomyocytes, GHMT-infected myocardium showed extensive beta-gal + non-cardiomyocytes and cardiomyocytes. Black boxes in top panels are enlarged i... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-12786
Applications
Tested Dilution
Publications
Product Specifications
Published species
Bovine,
Goat,
Guinea pig,
Human,
Mouse,
Pig,
Rabbit,
Rat,
Sheep
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
2B1.5
Immunogen
A purified preparation of lathyritic type II collagen from embryonic chicken sternum
Conjugate
Biotin
Biotin
Biotin
Form
Liquid
Concentration
0.2 mg/mL
Amount
100 µg
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
MA5-12786 targets Collagen II in FACS, IF, IHC (P), and WB applications and shows reactivity with Bovine, Chicken, Human, mouse, and Rat samples.
The MA5-12786 immunogen is a purified preparation of lathyritic type II collagen from embryonic chicken sternum.
Target Information
COL2A1 is the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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