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          • Primary Antibodies ›
          • SNRPB Antibodies
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          Invitrogen

          SNRPB Monoclonal Antibody (Y12), Biotin

          Advanced Verification
          14 References
          View all (9) SNRPB antibodies

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          Cite SNRPB Monoclonal Antibody (Y12), Biotin

          Additional Information:
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          • Antibody Testing Data (3)
          • Advanced Verification (1)
          SNRPB Antibody in Western Blot (WB)
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          SNRPB Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 4

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          SNRPB Antibody (MA5-13446) in WB

          Western blot analysis was performed on Nuclear enriched extracts (30 µg lysate) of HeLa (Lane 1), NTERA-2 (Lane 2), NIH/3T3 (Lane 3), Hep G2 (Lane 4), K-562 (Lane 5), SH-SY5Y (Lane 6), HEK-293 (Lane 7) and A-431 (Lane 8). The blots were probed with Anti-SNRPB Monoclonal Antibody (Product # MA5-13446, 1 µg/mL) and detected by chemiluminescence. A 24 kDa and 30 kDa band corresponding to Smith antigen was observed across the cell lines tested. Known quantity of protein samples were electrophoresed using Novex® NuPAGE® 4-12 % Bis-Tris gel (Pro... View More {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          SNRPB Antibody in Western Blot (WB)
          SNRPB Antibody in Western Blot (WB)
          SNRPB Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SNRPB Antibody

          Product Details

          MA5-13446

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1 µg/mL
          -

          Immunohistochemistry (IHC)

          -
          View 3 publications 3 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:100
          -

          Immunocytochemistry (ICC/IF)

          -
          View 5 publications 5 publications

          Immunoprecipitation (IP)

          -
          View 6 publications 6 publications

          Immunomicroscopy (IM)

          Assay-dependent
          -
          Product Specifications

          Species Reactivity

          Fruit fly, Human, Mouse, Pig, Rabbit, Rat

          Published species

          Dog, Fruit fly, Hamster, Human, Mouse

          Host/Isotype

          Mouse / IgG3, kappa

          Class

          Monoclonal

          Type

          Antibody

          Clone

          Y12

          Conjugate

          Biotin Biotin Biotin
          • Unconjugated
          • Request custom conjugation

          Form

          Liquid

          Concentration

          0.2 mg/mL

          Amount

          100 µg

          Purification

          Protein G

          Storage buffer

          PBS, pH 7.4, with 0.2% BSA

          Contains

          0.09% sodium azide

          Storage conditions

          4°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_10942935

          Target Information

          The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B') have been found for this gene.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: B polypeptide of Sm protein; Sm protein B; Sm protein B/B'; Sm-B; Sm-B/B'; sm-B/Sm-B'; SM11; small nuclear ribonucleoprotein particle (SmB'); small nuclear ribonucleoprotein particle (SmB); small nuclear ribonucleoprotein polypeptide B; small nuclear ribonucleoprotein polypeptides B and B'; Small nuclear ribonucleoprotein-associated protein B; Small nuclear ribonucleoprotein-associated proteins B and B'; smB; snRNP polypeptide B; snRNP-B; SNRPB; unnamed protein product

          View more View less

          Gene Aliases: AL024368; AU018828; CCMS; COD; SM-B; Sm-B/B'; SM11; SMB; SmB/B'; SmB/SmB'; SNRNP-B; SNRPB; SNRPB1

          View more View less

          UniProt ID: (Human) P14678, (Mouse) P27048, (Rat) P17136

          View more View less

          Entrez Gene ID: (Human) 6628, (Rabbit) 100341600, (Mouse) 20638, (Rat) 171365

          View more View less

          Function(s)
          RNA binding protein binding telomerase RNA binding snRNP binding histone pre-mRNA DCP binding U1 snRNP binding U2 snRNP binding poly(A) RNA binding RNA splicing factor
          Process(es)
          spliceosomal snRNP assembly mRNA splicing, via spliceosome mRNA processing protein methylation RNA splicing 7-methylguanosine cap hypermethylation U2-type prespliceosome assembly positive regulation of defense response to virus by host mitophagy in response to mitochondrial depolarization
          It has to be done as per old AB suggested Products section.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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