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Invitrogen
ITGA5 Monoclonal Antibody (10F6)
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Product Details
MA5-15568
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
10F6
Immunogen
Purified recombinant fragment of human ITGA5 expressed in E. Coli.
Conjugate
Form
Liquid
Concentration
Conc. Not Determined
Storage buffer
ascites
Contains
0.03% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
MA5-15568 targets ITGA5 in indirect ELISA, FACS, IHC, and WB applications and shows reactivity with Human samples.
The MA5-15568 immunogen is purified recombinant fragment of human ITGA5 expressed in E. Coli.
MA5-15568 detects ITGA5 which has a predicted molecular weight of approximately 114kDa.
Target Information
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CD49 antigen-like family member E; CD49e; Fibronectin receptor subunit alpha; fibronectin receptor, alpha polypeptide; fibronectin receptor, alpha subunit; Integrin alpha-5; Integrin alpha-F; integrin, alpha 5 (fibronectin receptor, alpha polypeptide); ITGA5/SLC9B1 fusion; surface glycoprotein receptor; unnamed protein product; very late activation protein 5, alpha subunit; VLA-5
Gene Aliases: CD49e; FNRA; ITGA5; VLA-5; VLA5A
UniProt ID: (Human) P08648
Entrez Gene ID: (Human) 3678
virus receptor activity
receptor binding
epidermal growth factor receptor binding
platelet-derived growth factor receptor binding
integrin binding
calcium ion binding
protein binding
signaling receptor activity
vascular endothelial growth factor receptor 2 binding
metal ion binding
cell adhesion molecule binding
angiogenesis
formation of primary germ layer
cell-substrate junction assembly
cell adhesion
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
leukocyte cell-cell adhesion
cell-matrix adhesion
integrin-mediated signaling pathway
female pregnancy
memory
tissue development
positive regulation of cell-substrate adhesion
response to muscle activity
CD40 signaling pathway
positive regulation of cell migration
positive regulation of vascular endothelial growth factor receptor signaling pathway
cell-substrate adhesion
cell adhesion mediated by integrin
cell-cell adhesion mediated by integrin
heterotypic cell-cell adhesion
wound healing, spreading of epidermal cells
endodermal cell differentiation
regulation of angiogenesis
viral entry into host cell
cell-cell adhesion
positive regulation of vascular endothelial growth factor signaling pathway
positive regulation of sprouting angiogenesis
negative regulation of anoikis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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