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Invitrogen
MESP1 Monoclonal Antibody (1A3)
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Product Details
MA5-15645
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1A3
Immunogen
Purified recombinant fragment of human MESP1 expressed in E. Coli.
Conjugate
Form
Liquid
Concentration
Conc. Not Determined
Storage buffer
ascites
Contains
0.03% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
MA5-15645 targets MESP1 in indirect ELISA, WB applications and shows reactivity with Human samples.
The MA5-15645 immunogen is purified recombinant fragment of human MESP1 expressed in E. Coli.
.
MA5-15645 detects MESP1 which has a predicted molecular weight of approximately 28.5kDa.
Target Information
Mesp1 (mesoderm posterior 1) is a basic helix-loop-helix-type transcription factor, which along with its related proteins, has an essential role in both segmentation and rostro-caudal patterning of somites in the anterior pre-somitic mesoderm. Mesp1 is expressed in many of the precursors of the cardiovascular system and is known to play a role in the process of cardiac morphogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: bHLHc5; Class C basic helix-loop-helix protein 5; mesoderm posterior 1 homolog; mesoderm posterior basic helix-loop-helix transcription factor 1; Mesoderm posterior protein 1; MGC10676
Gene Aliases: BHLHC5; MESP1
UniProt ID: (Human) Q9BRJ9
Entrez Gene ID: (Human) 55897
transcription regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
protein dimerization activity
sequence-specific double-stranded DNA binding
mesoderm formation
heart looping
heart morphogenesis
heart induction
secondary heart field specification
embryonic heart tube morphogenesis
cardiac atrium formation
cardiac ventricle formation
sinus venosus morphogenesis
growth involved in heart morphogenesis
cardioblast anterior-lateral migration
cardioblast migration
regulation of transcription from RNA polymerase II promoter
Notch signaling pathway
gastrulation
mesodermal cell migration
gene expression
neurogenesis
signal transduction involved in regulation of gene expression
somite rostral/caudal axis specification
negative regulation of mesodermal cell fate specification
negative regulation of endodermal cell fate specification
endothelial cell differentiation
positive regulation of Notch signaling pathway
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
lateral mesoderm development
positive regulation of striated muscle cell differentiation
cardiac muscle cell differentiation
cardiac cell fate determination
sinoatrial node cell differentiation
cardiac vascular smooth muscle cell differentiation
cardioblast migration to the midline involved in heart field formation
positive regulation of hepatocyte differentiation
negative regulation of canonical Wnt signaling pathway
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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