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          • Primary Antibodies ›
          • CD79a Antibodies

          Invitrogen

          CD79a Monoclonal Antibody (HM57), PE

          View all (83) CD79a antibodies

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          Cite CD79a Monoclonal Antibody (HM57), PE

          Additional Information:
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          CD79a Monoclonal Antibody (HM57), PE

          Product Details

          MA5-16711

          Applications
          Tested Dilution
          Publications

          Flow Cytometry (Flow)

          Neat
          -
          Product Specifications

          Species Reactivity

          Human, Many, Mouse, Rat

          Host/Isotype

          Mouse / IgG1

          Class

          Monoclonal

          Type

          Antibody

          Clone

          HM57

          Immunogen

          Synthetic peptide corresponding to 202-216 amino acid sequence of human mb-1.
          View immunogen

          Conjugate

          PE PE PE
          • Unconjugated
          • Request custom conjugation

          Excitation/Emission Max

          565/576 nm View spectra spectra

          Form

          Lyophilized

          Concentration

          Conc. Not Determined

          Purification

          Protein A

          Storage buffer

          PBS with 1% BSA, 5% sucrose

          Contains

          0.09% sodium azide

          Storage conditions

          4°C, store in dark, DO NOT FREEZE!

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2538203

          Product Specific Information

          Membrane permeabilization is required for flow cytometry applications. For FACS analysis, use 10 µL of the suggested working dilution to label 1x10^6 cells in 100 µL.

          Reconstitute with 1 mL of distilled water. After reconstitution, store product undiluted at 4°C in the dark. Once reconstituted, this product has a shelf life of approx. 18 months.

          Mouse anti Human CD79a antibody, clone HM57 recognizes an epitope within the cytoplasmic domain of CD79a.

          Target Information

          CD79a is a disulphide-linked heterodimer that includes B29 (CD79b) polypeptide. CD79a is a B lymphocyte antigen receptor with an antigen-specific surface component Ig (immunoglobulin) that associates with Ig-alpha and Ig-beta, necessary elements for the expression and function of the B-cell antigen receptor. CD79a first appears at pre-B cell stage and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type, in B cell lines, B cell lymphomas, and in some myelomas. It is not present in myeloid or T cell lines. Diseases associated with CD79a include Agammaglobulinemia 3 and Agammaglobulinemia, Non-Bruton type.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          How to use the Panel Builder

          Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: B-cell antigen receptor complex-associated protein alpha chain; B-cell antigen receptor complex-associated protein alpha chain-like; CD79; CD79a; CD79a antigen (immunoglobulin-associated alpha); CD79a molecule, immunoglobulin-associated alpha; extracellular domain; Ig alpha; Ig-alpha; immunoglobulin-associated alpha; MB-1 membrane glycoprotein; membrane-bound immunoglobulin associated protein; Membrane-bound immunoglobulin-associated protein; signal transduction via sig in B lymphocytes; putative; similar to Homo sapiens CD79A antigen (immunoglobulin-associated alpha) encoded by GenBank Accession Number U05259; Surface IgM-associated protein; unnamed protein product

          View more View less

          Gene Aliases: CD79A; Ig-alpha; IGA; IGAlpha; Ly-54; Ly54; MB-1; MB1

          View more View less

          UniProt ID: (Human) P11912, (Mouse) P11911

          View more View less

          Entrez Gene ID: (Human) 973, (Mouse) 12518, (Rat) 100913063

          View more View less

          Function(s)
          transmembrane signaling receptor activity protein binding identical protein binding immunoglobulin receptor superfamily
          Process(es)
          adaptive immune response immune system process cell surface receptor signaling pathway B cell differentiation B cell proliferation B cell activation B cell receptor signaling pathway
          It has to be done as per old AB suggested Products section.

          Disclaimer

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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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