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MA5-17407 targets CD5/Ly-1 in FACS applications and shows reactivity with Rat samples.
The MA5-17407 immunogen is rat thymocyte glycoproteins, depleted of LC-A, W3/13 antigen and Thy 1.
CD5 is a 67 kDa human T-lymphocyte single-chain transmembrane glycoprotein. CD5 is present on all mature T-lymphocytes, on most of thymocytes and on many T-cell leukemias and lymphomas. CD5 also reacts with a subpopulation of activated B-cells and may act as a receptor in regulating T-cell proliferation. CD5 is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. CD5 is expressed by many T cell leukemia, lymphomas, and activated T cells. Diseases associated with CD5 dysfunction include thymus cancer and Richter's Syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD antigen CD5; CD5; CD5 antigen; CD5 antigen (p56 62); CD5 antigen p56-62; fCD5; Ly12; LyA; Lymphocyte antigen CD5; Pan T cell; T-cell surface glycoprotein CD5
Gene Aliases: Cd5
UniProt ID: (Rat) P51882
Entrez Gene ID: (Rat) 54236
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