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Invitrogen
S100A9 Monoclonal Antibody (CF-557)
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FIGURE: 1 / 3
S100A9 Antibody (MA5-17624) in WB
Western blot was performed using Anti-S100A9 Monoclonal Antibody (Product # MA5-17624) and a 13kDa band corresponding to S100A9 was observed in THP-1 but was absent in Raji and SH-SY5Y which are reported to be negative. Expression of S100A9 was downregulated upon treatment of THP-1 with PMA/TPA [10.1073/pnas.0709958105]. Membrane enriched cell extracts (30 µg lysate) of THP-1 (Lane 1), THP-1 treated with PMA/TPA (50ng/ml for 24 hours) (Lane 2), Raji (Lane 3) and SH-SY5Y (Lane 4) were electrophoresed using Novex® NuPAGE® 4-12 % Bis-Tris gel... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-17624
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
CF-557
Immunogen
Purified granulocyte antigen of human origin
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
200 µg
Purification
Protein G
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
MA5-17624 targets Calgranulin B in FACS applications and shows reactivity with Human samples.
The MA5-17624 immunogen is purified granulocyte antigen of human origin.
Target Information
S100A9 (MRP-14) is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and altered expression of this protein is associated with the disease cystic fibrosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BM-009; calgranulin B; calprotectin L1H subunit; DKFZp686B04128; leukocyte L1 complex heavy chain; Macrophage; migration inhibitory factor-related protein 14; Monocyte; MRP-14; MRP15; MRP16; S100 A9; S100A9; unnamed protein product
Gene Aliases: 60B8AG; CAGB; CFAG; CGLB; L1AG; LIAG; MAC387; MIF; MRP14; NIF; P14; S100-A9
UniProt ID: (Human) P06702
Entrez Gene ID: (Human) 6280
leukocyte migration involved in inflammatory response
chronic inflammatory response
autophagy
inflammatory response
cell-cell signaling
positive regulation of neuron projection development
astrocyte development
positive regulation of cell growth
neutrophil chemotaxis
regulation of toll-like receptor signaling pathway
autocrine signaling
peptidyl-cysteine S-trans-nitrosylation
defense response to bacterium
endothelial cell migration
positive regulation of inflammatory response
defense response to fungus
regulation of cytoskeleton organization
regulation of respiratory burst involved in inflammatory response
antimicrobial humoral immune response mediated by antimicrobial peptide
neutrophil aggregation
positive regulation of intrinsic apoptotic signaling pathway
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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