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Invitrogen
H-2Kd/H-2Dd Monoclonal Antibody (34-1-2S), PE
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Product Details
MA5-18011
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
34-1-2S
Immunogen
BDF splenocytes
Conjugate
PE
PE
PE
Excitation/Emission Max
565/576 nm
View spectra
Form
Liquid
Concentration
0.1 mg/mL
Amount
50 µg
Purification
Protein G
Storage buffer
PBS with 4-5mg/mL BSA
Contains
0.02% sodium azide
Storage conditions
4°C, do not freeze
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
MA5-18011 targets H-2KdDd in FACS applications and shows reactivity with Mouse samples.
The MA5-18011 immunogen is bDF splenocytes.
Target Information
This protein is an MHC class I alloantigen, which is involved in antigen presentation to T cells expressing CD3/TCR and CD8.
HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alpha 1, 2, and 3 domains; class I major histocompatibility antigen H-2Kd; H-2 class I histocomatibility antigen, K-k alpha chain, topological domain; H-2 class I histocompatibility antigen, K-B alpha chain; H-2 class I histocompatibility antigen, K-D alpha chain; H-2 class I histocompatibility antigen, K-K alpha chain; H-2 class I histocompatibility antigen, K-Q alpha chain; H-2D cell surface glycoprotein; H-2K(B); H-2K(K); H-2K(Q); H2-DC1-beta transplantation antigen protein; H2-K; H2DD; H2K1; H2KD; histocompatibility 2, K region, promoter 1; MHC class I alpha chain; MHC class I antigen; MHC class I H-2Dp; MHC class I H2 antigen; MHC class I H2-K-b-alpha-2 cell surface glycoprotein; MHC class I heavy chain H2-K; MHC class I heavy chain heavy chain; MHC class I heavy chain maturation peptide; MHC class II antigen D; MHC class II antigen K; MHC H-2Dr; MHC H-2K integral membrane protein; MHC H-2K transplantation antigen; MHC H-2K-kml mRNA; MHC H2-D antigen; MHC H2-D-q alpha-chain; MHC H2-K antigen; MHC H2-K transplantation antigen; MHC H2-L transmembrane domain; ORF; Q5k protein; transmembrane protein; unnamed protein product
Gene Aliases: H-2D; H-2K; H-2K(d); H2-D; H2-D1; H2-K; H2-K1; K-f
UniProt ID: (Mouse) P01899, (Mouse) P01901
Entrez Gene ID: (Mouse) 14964, (Mouse) 14972
receptor binding
protein binding
beta-2-microglobulin binding
MHC class I protein binding
peptide antigen binding
T cell receptor binding
CD8 receptor binding
identical protein binding
protein homodimerization activity
natural killer cell lectin-like receptor binding
TAP binding
TAP1 binding
TAP2 binding
receptor agonist activity
chaperone binding
TAP complex binding
14-3-3 protein binding
positive regulation of T cell mediated cytotoxicity
antigen processing and presentation of endogenous peptide antigen via MHC class Ib
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent
immune response
signal transduction
negative regulation of neuron projection development
antigen processing and presentation
antigen processing and presentation of exogenous peptide antigen via MHC class I
defense response to bacterium
inner ear development
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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