Peptide Sequence: VRVARCCEDV CAHLVDLFLV EEIFQTAKET LQELQCFCKY LQRWREAVTA RKKLRRQMRA FPAAPCCVDV SDRLRALAPS AECPIAEENL ARGLLDLGHA
The minichromosome maintenance protein 3 (MCM3) is one of the MCM proteins essential for the initiation of DNA replication. The protein encoded by this gene is a MCM3 binding protein. It was reported to have phosphorylation-dependent DNA-primase activity, which was up-regulated in antigen immunization induced germinal center. This protein was demonstrated to be an acetyltransferase that acetylates MCM3 and plays a role in DNA replication. The mutagenesis of a nuclear localization signal of MCM3 affects the binding of this protein with MCM3, suggesting that this protein may also facilitate MCM3 nuclear localization.
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Protein Aliases: 80 kDa MCM3-associated protein; GANP; germinal center-associated nuclear protein; Germinal-center associated nuclear protein; germinal-centre associated nuclear protein; MAP80; MCM3 acetylating protein; MCM3 acetyltransferase; MCM3 import protein; MCM3 minichromosome maintenance deficient 3 associated protein; MCM3AP; minichromosome maintenance deficient 3-associated protein
Gene Aliases: GANP; KIAA0572; MAP80; MCM3AP; SAC3
UniProt ID: (Human) O60318
Entrez Gene ID: (Human) 8888