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Invitrogen
ITGB8 Monoclonal Antibody (416922), APC
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Product Details
MA5-23674
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
416922
Immunogen
Mouse myeloma cell line NS0-derived recombinant human Integrin beta 8 Glu43-Arg684 (predicted)
Conjugate
Excitation/Emission Max
651/660 nm
View spectra
Form
Liquid
Purification
Protein A/G
Storage buffer
Buffered saline solution with ≤ 0.5% BSA
Contains
0.09% sodium azide
Storage conditions
4°C, store in dark, DO NOT FREEZE!
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
In direct ELISAs, no cross-reactivity with recombinant human Integrins beta 1, beta 2, beta 3, beta 4, beta 5, beta 6 beta 7, or recombinant mouse Integrin beta 8 is observed.
Target Information
ITGB8 (Integrin beta 8) is a member of the integrin beta chain family and is a single-pass type I membrane protein with a VWFA domain and four cysteine-rich repeats. This protein noncovalently binds to an alpha subunit to form a heterodimeric integrin complex. In general, integrin complexes mediate cell-cell and cell-extracellular matrix interactions and this complex plays a role in human airway epithelial proliferation. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Integrin beta-8; Integrin beta8; unnamed protein product
Gene Aliases: ITGB8
UniProt ID: (Human) P26012
Entrez Gene ID: (Human) 3696
vasculogenesis
ganglioside metabolic process
immune response
cell adhesion
cell-matrix adhesion
cell surface receptor signaling pathway
transforming growth factor beta receptor signaling pathway
integrin-mediated signaling pathway
response to virus
positive regulation of gene expression
negative regulation of gene expression
cell migration
cell differentiation
cell adhesion mediated by integrin
positive regulation of angiogenesis
cartilage development
hard palate development
placenta blood vessel development
Langerhans cell differentiation
cell-cell adhesion
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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