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Invitrogen
GARS Monoclonal Antibody (OTI6C5)
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FIGURE: 1 / 6
GARS Antibody (MA5-26714) in IHC (P)
Immunohistochemistry was performed on paraffin-embedded adenocarcinoma of human colon tissue. To expose target proteins, 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min was used. Following antigen retrieval, tissues were probed with a GARS monoclonal antibody (Product # MA5-26714).
Product Details
MA5-26714
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
OTI6C5
Immunogen
Full length human recombinant protein of GARS produced in HEK293T cell
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
GARS is a glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. This protein is an (alpha)2 dimer which belongs to the class II family of tRNA synthetases. The protein has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 6.1.1.14; AIR synthase; AIRS; AP-4-A synthetase; Ap4A synthetase; Charcot-Marie-Tooth neuropathy 2D; Charcot-Marie-Tooth neuropathy, neuronal type, D; Diadenosine tetraphosphate synthetase; EC 2.1.2.29; GAR transformylase; GART; GARTF; Glycine--tRNA ligase; Glycyl-tRNA synthetase; Glycyl-tRNA synthetase 1; GlyRS; MGC47764; PAIS; PGFT; PRGS; unnamed protein product
Gene Aliases: CMT2D; DSMAV; GARS; GARS1; GlyRS; HMN5; HMN5A; HMND5; SMAD1; SMAJI
UniProt ID: (Human) P41250
Entrez Gene ID: (Human) 2617
nucleotide binding
bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity
aminoacyl-tRNA ligase activity
glycine-tRNA ligase activity
protein binding
ATP binding
transferase activity
hydrolase activity
ligase activity
identical protein binding
protein dimerization activity
ATP:ATP adenylyltransferase activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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