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Invitrogen
BTG1 Monoclonal Antibody (OTI7H6)
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FIGURE: 1 / 5
BTG1 Antibody (MA5-26923) in IHC (P)
Immunohistochemistry was performed on paraffin-embedded adenocarcinoma of human endometrium tissue. To expose target proteins, 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min was used. Following antigen retrieval, tissues were probed with a BTG1 monoclonal antibody (Product # MA5-26923).
Product Details
MA5-26923
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI7H6
Immunogen
Full length human recombinant protein of BTG1 produced in E.coli
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
BTG1 is a member of an anti-proliferative gene family that regulates cell growth and differentiation. Expression of this gene is highest in the G0/G1 phases of the cell cycle and downregulated when cells progressed through G1. The encoded protein interacts with several nuclear receptors, and functions as a coactivator of cell differentiation. This locus has been shown to be involved in a t(8; 12)(q24; q22) chromosomal translocation in a case of B-cell chronic lymphocytic leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: B-cell translocation gene 1 protein; B-cell translocation gene 1, anti-proliferative; BTG1; Protein BTG1; unnamed protein product
Gene Aliases: APRO2; BTG1
UniProt ID: (Human) P62324
Entrez Gene ID: (Human) 694
regulation of transcription, DNA-templated
response to oxidative stress
spermatogenesis
cell proliferation
negative regulation of cell proliferation
cell migration
negative regulation of cell growth
response to peptide hormone
positive regulation of endothelial cell differentiation
positive regulation of myoblast differentiation
positive regulation of angiogenesis
positive regulation of fibroblast apoptotic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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