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Invitrogen
CD104 (Integrin beta 4) Monoclonal Antibody (450-9D), FITC
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Product Details
MA5-28117
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
450-9D
Immunogen
Purified alpha6 beta4 integrin from A431 cells
Conjugate
Excitation/Emission Max
498/517 nm
View spectra
Form
Liquid
Concentration
0.1 mg/mL
Amount
100 µg
Purification
Protein G
Storage buffer
PBS with 1% BSA
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody recognizes an extracellular epitope on the CD104 molecule.
Target Information
Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD antigen CD104; CD104; CD104 antigen; GP150; Integrin beta-4; unnamed protein product
Gene Aliases: CD104; GP150; ITGB4; JEB5A; JEB5B
UniProt ID: (Human) P16144
Entrez Gene ID: (Human) 3691
autophagy
cell communication
cell adhesion
cell-matrix adhesion
integrin-mediated signaling pathway
response to wounding
cell migration
myelination in peripheral nervous system
hemidesmosome assembly
peripheral nervous system myelin formation
cell adhesion mediated by integrin
nail development
skin morphogenesis
filopodium assembly
mesodermal cell differentiation
cell motility
trophoblast cell migration
cell-cell adhesion
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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