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Invitrogen
CD323 (JAM3) Monoclonal Antibody (CRAM-18 F26)
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Product Details
MA5-28231
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rat
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
CRAM-18 F26
Immunogen
Recombinant soluble JAM-C
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Rat anti Mouse JAM-c antibody, clone CRAM-18 F26 recognizes mouse and human Junctional adhesion molecule C (JAM-C), also known as JAM-3 and, historically, as JAM-2.
Target Information
JAM3 is involved in tight junctions and represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. Unlike other proteins in this family, the this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions. The encoded protein is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: JAM-2; JAM-3; JAM-C; junction cell adhesion molecule 3; junction cell adhesion molecule C; Junctional adhesion molecule 3; Junctional adhesion molecule C
Gene Aliases: 1110002N23Rik; JAM-3; JAM-C; Jam3; Jcam3
UniProt ID: (Mouse) Q9D8B7
Entrez Gene ID: (Mouse) 83964
angiogenesis
neutrophil homeostasis
adaptive immune response
myeloid progenitor cell differentiation
leukocyte migration involved in inflammatory response
cell adhesion
cell-matrix adhesion
spermatogenesis
spermatid development
cell migration
transmission of nerve impulse
establishment of cell polarity
myelination
regulation of neutrophil chemotaxis
regulation of actin cytoskeleton organization by cell-cell adhesion
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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