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Invitrogen
CD45RO Monoclonal Antibody (IL-A116)
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FIGURE: 1 / 1
CD45RO Antibody (MA5-28403) in Flow
Flow cytometry of CD45RO in red cell lysed bovine blood. Sample was incubated in the presence of 10% rat serum, CD45RO monoclonal antibody (Product # MA5-28403) and gated on lymphoid cells. Figures are arranged as follows: A) FITC conjugated Mouse anti Bovine CD4 Antibody and RPE conjugated Mouse IgG3 isotype control. B) FITC conjugated Mouse anti Bovine CD4 Antibody and RPE conjugated Mouse anti Bovine CD45RO Antibody.
Product Details
MA5-28403
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine
Host/Isotype
Mouse
/ IgG3
Class
Monoclonal
Type
Antibody
Clone
IL-A116
Immunogen
Bovine peripheral blood mononuclear cells
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Mouse anti Bovine CD45RO, clone IL-A116 recognizes the bovine homologue of the human CD45RO cell surface antigen.
Target Information
CD45RO (UCHL1, ubiquitin carboxyl terminal esterase L1) is the shortest isoform of a receptor-type protein tyrosine phosphatase, CD45 glycoprotein. CD45 is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases, promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis. CD45 isoforms differ in their extracellular domains, whereas they share identical transmembrane and cytoplasmic domains. CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell. CD45RO is expressed on macrophages, CD8+ T cells, activated T cells and myeloma cells. Besides the role in immunoreceptor signaling, CD45 is important in promoting cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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