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Invitrogen
FOLR2 Monoclonal Antibody (EM-35)
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Product Details
MA5-28552
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
EM-35
Immunogen
BW5147alpha,beta- cells
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
15mM sodium azide
Storage conditions
4°C, do not freeze
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody recognizes an extracellular epitope on FOLR2, a 30-40 kDa cell surface protein serving as a receptor for folic acid.
Western Blot: non-reducing conditions.
Target Information
FOLR2 is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FBP; Folate receptor 2; folate receptor 2 (fetal); folate receptor alpha; Folate receptor beta; Folate receptor, fetal/placental; folate-binding protein, fetal/placental; FR-beta; Placental folate-binding protein
Gene Aliases: BETA-HFR; FBP; FBP/PL-1; FOLR1; FOLR2; FR-BETA; FR-P3; FRbeta
UniProt ID: (Human) P14207
Entrez Gene ID: (Human) 2350
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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