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Invitrogen
RRAS2 Monoclonal Antibody (EM-50), PE
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FIGURE: 1 / 1
RRAS2 Antibody (MA5-28615) in Flow
Separation of R-Ras2 transfected HEK-293 cells (red) from nontransfected HEK-293 cells (blue) in flow cytometry analysis (intracellular staining) stained using anti-R-RAS2 (EM-50) PE Monoclonal antibody (Product # MA5-28615), concentration in sample 1 µg/mL.
Product Details
MA5-28615
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
EM-50
Immunogen
Human TC21
Conjugate
Excitation/Emission Max
565/576 nm
View spectra
Form
Liquid
Concentration
0.1 mg/mL
Amount
100 µg
Purification
Size-exclusion chromatography
Storage buffer
PBS, pH 7.4, with 0.2% BSA
Contains
15mM sodium azide
Storage conditions
4°C, store in dark, DO NOT FREEZE!
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody recognizes R-Ras2 / TC21 protein (intracellular antigen) and does not react with R-Ras1, H-Ras, K-Ras, and N-Ras.
Target Information
RRAS2 is involved in activating mutations and the overexpression of classical Ras subfamily members (K-RAS, N-RAS and H-RAS) have been widely investigated as key events in the development of human cancers. The RRAS subfamily of Ras-related proteins includes RRAS1, RRAS2 (TC21) and RRAS3 (M-Ras) show overall amino acid identity with the classical Ras subfamily (H-Ras, K-Ras and N-Ras) of 55-60%. RRAS2 is a small GTP binding protein of the Ras superfamily of GTPases. It might transduce growth inhibitory signals across the cell membrane, exerting its effect through an effector shared with the Ras proteins. RRAS2 has high oncogenic potential and overexpression/mutations have been reported in several tumor tissues and cell lines.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ras-like protein; Ras-like protein TC21; Ras-related protein R-Ras2; related RAS viral (r-ras) oncogene homolog 2; small GTP binding protein; Teratocarcinoma oncogene; unnamed protein product
Gene Aliases: NS12; RRAS2; TC21
UniProt ID: (Human) P62070
Entrez Gene ID: (Human) 22800
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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